Hi! I don't see a separate bug topic or something like that, so I'll dump everything here. (Everything below is from academic playthrough, if that matters).
1) NPCs are not persistent, and so they are re-randomized on page reload. Relationships remain... in a way (they disappear from the sidebar, but numerical values are still there when you meet the re-randomized NPC again).
2) Some travel links are wrong; most places in civic square have backlinks to a guild row instead. Port and waterfront are weirdly mixed up; most places in waterfront have backlinks back to it but seeking work makes you end up in port. Some travel links in the southern part of sewers are also broken.
3) Adventurer guild quests supposedly give you +1 agility or +1 charisma or something, but there's no visible increase? (also what does +1 even mean, is it +1 level, which is a lot, or +1 exp, which is negligible?)
4) Merchant guild quests do not have the option to actually complete them (no link whatsoever in the guild travel menu, compared to the Adventurer guild)
5) Success/failure in conversations seemingly doesn't matter; e.g. you gain +2 to relationship and some persuasion/performance exp both when your joke is good and when it isn't (which is great for exp farming btw).
The game is nice, though!